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Allogenic simple limbal epithelial transplantation (alloSLET) from cadaveric donor eyes in patients with persistent corneal epithelial defects

2020

Background/aimTo describe the clinical outcome of allogenic simple limbal epithelial transplantation (alloSLET) utilising tissue from cadaveric donor eyes after failed re-epithelialisation of the corneal surface.MethodsMedical records of 14 eyes from 14 patients treated for persistent corneal epithelial defects with alloSLET were reviewed. The primary outcome measure was complete epithelialisation of the corneal surface. Secondary outcome measures were best corrected visual acuity (BCVA) and postoperative side effects due to surgery or medical therapy.ResultsOf the 14 eyes, 7 received alloSLET only and 7 alloSLET together with penetrating keratoplasty (PK). Thirteen (92.9%) of 14 eyes had a…

AdultMalemedicine.medical_specialtygenetic structuresPrednisoloneVisual AcuityLimbus CorneaeCorneal DiseasesCellular and Molecular NeuroscienceRe-EpithelializationCorneaOphthalmologyCadaverHumansMedicineEffective treatmentIn patientAgedRetrospective StudiesCorneal epitheliumAged 80 and overbusiness.industryEpithelium CornealCadaveric donorMiddle AgedMycophenolic AcidAllograftsTissue Donorseye diseasesSensory SystemsTransplantationOphthalmologyTreatment Outcomemedicine.anatomical_structureFemalesense organsbusinessBandage contact lensOcular surfaceImmunosuppressive AgentsBritish Journal of Ophthalmology
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